Unique HPLC purified peptides for sensitive applications

This month, Biorbyt introduced four new high quality peptides for use in applications requiring >95% purity such as biochemical applications or quantitative assays.

All four products are available as freeze-dried solids, are soluble in water, and purified by HPLC to be >95% pure:

KP1

Represents the sequence Phe57 to Lys86 of the anti-aging protein Klotho, that disrupts TGF-β/TβR2 interaction.

Catalog number: orb1147094

Rytvela

IL-1 receptor allosteric antagonist which is an all D peptide derived from an extracellular loop region of the interleukin-1 receptor accessory protein (IL-1RAcP).

Catalog number: orb1147046

SHBG 141-161

Corresponds to amino acids 141–161 of sex hormone binding globulin (SHBG), the loop region of SHBG connecting β-strands 11 and 12. Acts as an agonist of the class C orphan G protein coupled receptor GPRC6A.

Catalog number: orb1147041

TPP-1

Identified through bacterial surface display, binds specifically to programmed cell death ligand 1 (PD-L1), and blocks programmed cell death protein 1 (PD-1)/PD-L1 interaction.

Catalog number: orb1147028

Peptides

Peptides are used for a wide range of applications, e.g., protein-protein interaction studies, to investigate modification sites within proteins, as enzyme substrates, as immunogens for antibody production, as ligands for protein purification, and as blocking peptides for assay development.

While a peptide that is >70% pure is acceptable for many immunological applications, more sensitive applications such as interaction studies or quantitative bioassays may require HPLC purification to produce peptides that are >95% pure.

Whether you are looking for a blocking peptide or a high purity receptor agonist, Biorbyt’s product datasheets give you the information you need to make the best choice for your application.

Bio-Connect Life Sciences supplies all Biorbyt products in the Benelux. If you have any questions, please contact the helpdesk.