Enzo Spatial Biology – Enabling Flexible Multiomics Analysis

Enzo’s multiplexing solutions empower researchers to extract more data from every sample—without sacrificing clarity, sensitivity, or specificity. Understanding cell–cell interactions, microenvironment dynamics, and disease mechanisms often requires analyzing multiple biomarkers simultaneously within the same tissue section.

With Enzo’s multiplexing solutions, researchers can:

• Visualize multiple markers simultaneously within a single section
• Preserve spatial relationships between RNA and proteins
• Identify rare cell populations and functional states in heterogeneous tissues
• Maximize data from precious clinical samples or small biopsies

Whether using singleplex or multiplex assays, automated or manual protocols, and fluorescence or chromogenic detection, our flexible and adaptable solutions cater to diverse research needs.

Nucleic Acid Detection – AMPIVIEW® RNA Probes
Protein Detection – Antibodies
Cellular Detection – CELLESTIAL® Cell-based Assays

Multiplexing Solutions for Spatial Biology – Simultaneously analyze multiple targets, including nucleic acids, proteins, and organelles. Perform multiplexing individually or combine targets for comprehensive insights.

Multiplex ISH/IF

Nestin protein (red) and non-long coding RNA NORAD (green) detected in rat brain tissue. Co-localization of nestin and NORAD (yellow) is seen in this sample.

Multiplex ISH/IHC

(A) Detection of p16 (red). (B) Detection of HPV with AMPIVIEW® High-Risk HPV RNA probe (brown). (C) p16 and high-risk HPV detection with p16 antibody (red) and AMPIVIEW HPV High-Risk RNA probes (brown) in HPV infected cervical tissue.